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| First Round Draft Pick History |
| 1 | 10 | 10 | 2000 | Annual Draft | P | Bronson | Arroyo | MLB |
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| Complete Draft History |
| 1 | 10 | 10 | 2000 | Annual Draft | P | Bronson | Arroyo | MLB |
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| 2 | 10 | 34 | 2000 | Annual Draft | P | Paul | Wilson | MLB |
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| 2 | 19 | 43 | 2000 | Annual Draft | 2B+ | Luis | Alicea | MLB |
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| 3 | 10 | 58 | 2000 | Annual Draft | 1B+ | Chris | Richard | MLB |
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| 4 | 10 | 82 | 2000 | Annual Draft | OF | Jason | Tyner | MLB |
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| 5 | 10 | 106 | 2000 | Annual Draft | P | Scott | Mullen | MLB |
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| 6 | 10 | 130 | 2000 | Annual Draft | P | Dennis | Cook | MLB |
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| 7 | 10 | 154 | 2000 | Annual Draft | P | Jeff | Sparks | MLB |
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| 8 | 10 | 178 | 2000 | Annual Draft | C | Danny | Ardoin | MLB |
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| 9 | 10 | 202 | 2000 | Annual Draft | P | Scott | Winchester | MLB |
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| 10 | 10 | 226 | 2000 | Annual Draft | P | Rich | Sauveur | MLB |
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| 11 | 10 | 250 | 2000 | Annual Draft | C | Yohanny | Valera | MLB |
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| 12 | 10 | 274 | 2000 | Annual Draft | OF | Reggie | Taylor | MLB |
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| 13 | 10 | 298 | 2000 | Annual Draft | P | David | Maurer | MLB |
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| 14 | 10 | 322 | 2000 | Annual Draft | P | Sang-Hoon | Lee | MLB |
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| 15 | 10 | 346 | 2000 | Annual Draft | P | Cameron | Cairncross | MLB |
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